- Drug Class Description
- Generic Name
Skinoren cream 1 g contains 200 mg (20%) micronised azelaic acid.
Topical treatment of acne vulgaris.
- Adult Dosage
Skinoren should be applied to the affected areas twice daily (mornings and evenings), and rubbed in well. Regular use is important.
Patients with sensitive skin should be advised to use Skinoren only once a day (in the evening) for the first week of treatment and then proceed to twice daily applications.
Before Skinoren is applied, the skin should be thoroughly washed with water alone or, if necessary, with a mild cleansing agent.
The amount of Skinoren to be applied will depend on the size of the affected area. As a guide a daily dose of 2 g (1 g per application) will be sufficient for the treatment of the entire facial area (1 g = 4 cm cream).
If other areas of acne, in addition to the face require treatment, for example the chest and back, a daily dose of 10 g of cream should not, in general, be exceeded.
The duration of use of Skinoren will vary from person to person and also depends on the severity of the acne. In general, a distinct improvement becomes apparent after about 4 weeks. To obtain the best results, Skinoren should be applied over a period of several months but not for more than 6 months.
- Contra Indications
Hypersensitivity to any ingredient of the cream, in particular propylene glycol.
- Special Precautions
For external use only.
Avoid contact with the eyes. If Skinoren comes into contact with the eyes they should immediately be thoroughly rinsed with copious amounts of water.
Skinoren contains a small amount of benzoic acid, which is mildly irritating to the skin, eyes and mucous membrane.
Skinoren also contains propylene glycol, which may cause skin irritation.
- Adverse Drug Reactions
Local skin irritation (e.g. erythema, scaling, itching or burning) occurs in occasional cases, usually at the start of treatment. However, in the majority of cases the irritation is mild and regresses as treatment continues. If marked skin irritation persists, the amount of cream per application should be reduced, the frequency of application should be reduced, or the treatment temporarily interrupted until the symptoms regress.
Photosensitivity reactions have been reported very rarely during the use of Skinoren.
Also, in very rare cases, allergic skin reactions (e.g. rash) may occur